ethyl palmitate

• ethyl palmitate is a naturally occurring fatty acid ester formed by the reaction of palmitic acid and ethanol. it is found in small amounts in plant oils, animal fats, and fermented foods, and is also synthesized for use in cosmetics, food, and pharmaceutical applications. ethyl palmitate is valued for its emollient, solvent, and potential bioactive properties.

chemical and physical properties

• compound type: ester (ethyl ester of palmitic acid)
• molecular weight: 270.45 g/mol
• chemical formula: C₁₈H₃₆O₂
• boiling point: ~215–220°C at reduced pressure
• solubility: insoluble in water; soluble in organic solvents and oils
• appearance: clear to pale yellow liquid

usefulness in medicine and industry

• used as an emollient in cosmetic formulations for skin-softening and skin moisturizing effects.
• serves as a solvent or carrier for lipophilic drugs in topical and transdermal delivery systems.
• employed in the food industry as a flavoring agent or fat-soluble excipient.
• may exhibit mild anti-inflammatory or antioxidant effects based on early studies.
• considered biodegradable and environmentally friendly, making it suitable for use in green chemistry.

antibacterial and antimicrobial activity

• limited studies suggest ethyl palmitate may inhibit certain bacterial growth, especially when formulated with other active agents.
• contributes to barrier-enhancing effects in skin, supporting protection against microbial invasion.
• research highlights:
• bacteria:
  • staphylococcus aureus research link
  • escherichia coli research link

research links

• ethyl palmitate in cosmetics
• ethyl palmitate pharmacological effects
• ethyl palmitate antimicrobial properties