maximum amount of a substance (solute) that dissolves in a given solvent at a specific temperature

"like dissolves like": polar solutes dissolve in polar solvents (water), nonpolar in nonpolar

measured in g/L or mol/L

increases with temperature for most solids; gases become less soluble as temperature rises

pressure affects gas solubility (Henry's law): higher pressure, more gas dissolves

saturation, supersaturation, and precipitation describe solution states

solubility of minerals in water drives weathering, cave formation, and nutrient cycling

drug solubility determines bioavailability in pharmacology

solubility product (Ksp) quantifies equilibrium for sparingly soluble salts

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