• diisooctyl phthalate (diop or dioctyl isophthalate) is a synthetic phthalate ester widely used as a plasticizer to increase the flexibility, transparency, and durability of plastics, particularly in polyvinyl chloride (pvc) products. it is a colorless, oily liquid with low volatility and is primarily used in industrial and commercial applications.

chemical and physical properties

  • compound type: aromatic diester (phthalate)
  • molecular weight: 390.57 g/mol
  • chemical formula: C₂₄H₃₈O₄
  • boiling point: ~385°C
  • solubility: insoluble in water; soluble in most organic solvents
  • appearance: clear, oily liquid with mild odor

industrial uses and exposure

  • extensively used as a plasticizer in pvc-based materials such as cables, flooring, hoses, artificial leather, and coatings.
  • found in products like adhesives, paints, sealants, and rubber compounds.
  • used in medical devices, although being phased out in favor of safer alternatives due to potential toxicity concerns.
  • exposure occurs mainly through inhalation, ingestion, or dermal contact, especially in occupational settings.

health and environmental concerns

  • studies suggest potential for endocrine disruption, particularly affecting reproductive and hormonal systems in animals.
  • bioaccumulation is low, but it may persist in soil and sediment, leading to long-term environmental contamination.
  • regulatory agencies in some countries have restricted or banned its use in toys, childcare articles, and certain packaging.
  • ongoing evaluation for safer plasticizer alternatives is encouraging its replacement in many consumer products.
  • research highlights:
  • toxicological studies: