dibutyldimethylurea

• dibutyldimethylurea is a synthetic urea derivative characterized by two butyl and two methyl groups attached to a central urea structure. it is a chemically modified compound with reported antimicrobial and antifungal properties, and has been identified in the root extracts of certain medicinal plants. although not naturally abundant, it may serve as a lead compound for developing new antibacterial agents.

chemical properties

• molecular weight: 230.37 g/mol
• structure: symmetrical urea molecule substituted with two butyl and two methyl groups
• appearance: white to off-white crystalline solid (depending on purity)
• solubility: soluble in organic solvents such as ethanol, ether, and chloroform; poorly soluble in water
• chemical formula: C₁₀H₂₂N₂O

usefulness in medicine

• dibutyldimethylurea has shown potential antimicrobial activity in early screening studies.
• it may act as a membrane disruptor or enzyme inhibitor, although its mechanism is not well-characterized.
• due to its urea backbone, it may be investigated for urease inhibition in microbial pathogens.
• its bioactivity is of interest in natural product chemistry and drug development from plant-derived compounds.

antibacterial and antimicrobial activity

• it has been shown to inhibit growth of certain gram-positive and gram-negative bacteria in vitro.
• some studies suggest potential action against fungal pathogens such as candida species.
• may work synergistically with other phytochemicals in plant extracts.
• research highlights:
• bacteria:
  • escherichia coli research link
  • bacillus subtilis research link
• fungi:
  • candida albicans research link

research links

• dibutyldimethylurea antimicrobial activity
• urea derivatives in drug discovery
• plant-derived urea compounds